Publications

1. KT. Wagner, S Landau, GM. Kent, DF. Bodenstein, M Radisic. “Mapping the miRNA landscape of primitive macrophage extracellular vesicles highlights their pro-vasculogenic effects in engineered human cardiac tissue”. APL Bioengineering (submitted) 
    

2. Y Wang , C Dikyol, K T Wagner, S Landau, C Liu, S Okhovatian, DF Bodenstein, D Vosoughi, Y Zhao, K Shen, A Shakeri, Q Wu, M Radisic. “3D fractal topography attenuates inflammation and confers resilience to glomerular podocytes”. Cell Biomaterials (in press)
    

3. Liu C, P Aggarwal, KT Wagner, S Landau, Teng, Y Zhao, et al. “Biomimetic fractal topography enhances podocyte maturation in vitro”. Nature comm. (2025)
    

4. Y Zhao, R Khosravi, K Cheung, K Shen, Y Wang, S Landau, S Okhovatian, Q Wu, R X Lu, K T Wagner, D Bodenstein, S A. Shawky, D Vosoughi, E L Beroncal, K Yeager, C L Cummins, A C Andreazza, G Vunjak-Novakovic and Milica Radisic. “Geometrically controlled cardiac microtissues promote vascularization and reduce inflammation in vitro and in vivo”. Cell Biomaterials (2025)
    

5. S L Kracoff-Sella, I Goldfracht, A Silverstein, S Landau, L Debbi, R Beckerman, H Shoyhat, Y Herman-Bachinsky, G Guterman-Ram, I Michael, R Shuhmaher, J Zavin, R Ben-Horin, ‪ D Egozi‏, S Levenberg. “Rational design of 3D-printed scaffolds for breast tissue engineering using structural analysis”.Biofabrication 17 (2), (2025). 
    

6. S Landau*, J Kieda*, S Okhovatian, K Ramsay, C Liu, S Tsai and M Radisic. “Cell driven elastomeric particle packing in composite granular bioinks for engineering of stable 3D printed structures”. Bioactive materials 44, 411-427 (2025)
    

7. S Landau, S Okhovatian, Y Zhao, C Liu, A Shakeri, Y Wang, K Ramsay, J Kieda, R Jiang, and M Radisic. “Bioengineering vascularization” Development 151 (23). (2025)
    

8. R Lu, Wagner KT, S Landau, SA Shawky, Y Zhao, et al. “Endothelial extracellular vesicles enhance vascular self-assembly in human engineered cardiac tissues”. Biofabrication 16 (4), 045037 (2025).
    

9. S Landau*, Y Zhao*, G Kent, S Okhovatian, R Lu, C Liu, KT Wagner, K Cheung, H Hamidzada, SA Shawky, D Vosoughi, EL Beroncal, I Fernandes, CL Cummins, AC Andreazza, G M Keller, S Epelman and M Radisic. “Primitive macrophages enhance a perivascular niche to enable vascular perfusion in human cardiac tissue”. Cell Stem Cell (2024).
    

10. Q Wu, N Rafatian, KT. Wagner, J Blamer, J Smith, S Okhovatian, P Aggarwal, EY Wang, A Banerjee, Y Zhao, RX Lu, LP Esquivel, C Yu Li, U Kuzmanov, S Mandla, E Virlee, S Landau, BF Lai, A Gramolini, C Liu, Sharon Fleisher, T Veres, G Vunjak-Novakovic, B Zhang, K Mossman, U Broeckel, M Radisic. “SARS-CoV-2 pathogenesis in angiotensin II induced heart-on-a-chip disease model and exosome screening”. PNAS 121 (28), e2403581121 (2024).
     

11. Y Zhao*, S Landau*, S Okhovatian1, C Liu, R Lu, BF Lai, Q Wu, J Kieda1, K Cheung, S Rajasekar, K Jozani, B Zhang, M Radisic. “Integrating organoids and organ-on-a-chip devices”. Nature Reviews Bio-Engineering. 1-21 (2024)
     

12. S Landau, E Shor, M Radisic, S Levenberg. “Quantitative image analysis of tissue properties: a MATLAB tool for measuring morphology and co-localization in 2D images”. bioRxiv, 2024.04. 03.587971 (2024)
     

13. S Levenberg, S Landau, S Duvdevani. “Auricular reconstruction using 3d printed autologous cartilage tissue.” US Patent App. 18/270,852. (2024)
     

14. H Hamidzada *, S Pascual-Gil,* , Q Wu, G Kent, M H., Atkins, S Massé, S Landau, M. J Gomez-Garcia, C Kantores, E Beroncal, N Rafatian, J Nanthakumar, E Y. Wang, T V. Sadikov, A C. Andreazza, K Nanthakumar , M A. Laflamme, G Keller, M Radisic and Slava Epelman. “Primitive macrophages enhance the function of bioengineered human cardiac microtissues”. Nature Cardiovascular Research, 1-27. (2024)
     

15. D Bannerman, S P Gil de Gomez, Q Wu, I Fernandes, Y Zhao, K Wagner, S Okhovatian, S Landau, N Raftian, T R. Nash, G Vunjak-Novakovic, G Keller, S Epelman, M Radisic. “Heart-on-a-chip model of epicardial-myocardial interaction in ischemia reperfusion injury.” Advanced Health Care Materials. 2302642. (2024)
     

16. A Shakeri, Y Wang, Y Zhao, S Landau, K Perera, J Lee, M Radisic. “Engineering Organ-on-a-Chip Systems for Vascular Diseases”. Arteriosclerosis, Thrombosis, and Vascular Biology, 43 (12), 2241-2255. (2023)
     

17. J Kieda, A Shakeri, S Landau, EY Wang, Y Zhao, BF Lai, S Okhovatian, Y Wang, R Jiang, M Radisic. “Advances in cardiac tissue engineering and heart‐on‐a‐chip”. Journal of Biomedical Materials Research Part A, (2023).
     

18. M Wauchop, N Rafatian, Y Zhao, W Chen, M Gagliardi, S Massé, B J Cox, P Lai, T Liang, S Landau, S Protze, XD Gao, EY Wang, KC Tung, Z Laksman, R Xing Ze Lu, G Keller, K Nanthakumar, M Radisic, PH Backx. “Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation”. Biomaterials. 301, 122255. (2023)
     

19. Q Wu, P Zhang, G O’Leary, Y Zhao, Y Xu, N Rafatian, S Okhovatian, S Landau, T A Valiante, J Travas-Sejdic, M Radisic. “Flexible 3D printed microwires and 3D microelectrodes for heart-on-a-chip engineering”. Biofabrication, 035023. (2023)
     

20. G Chen, R Levin, S Landau, M Kaduri, O Adir, I Ianovici, N Krinsky, O Doppelt-Flikshtain, J Shklover, J Shainsky-Roitman, S Levenberg, A Schroeder. “Implanted synthetic cells trigger tissue angiogenesis through de novo production of recombinant growth factors”. PNAS 119 (38), e2207525119. (2022)
     

21. Y Zagury, I Ianovici, S Landau, N Lavon, S Levenberg. “Engineered marble-like bovine fat tissue for cultured meat”. Communications Biology.  5 (1), 927, (2022)
     

22. I Redenski, S Guo, M Machour, A Szklanny, S Landau, D Egozi, Y Gabet, S Levenberg. “Microcomputed Tomography-Based Analysis of Neovascularization within Bioengineered Vascularized Tissues”. ACS Biomaterials Science & Engineering. 8 (1), 232-24, (2021)
     

23. S Landau, A Szklanny, M Machour, B Kaplan, Y Shandalov, I Redenski, M Beckerman, O Harari-Steinberg, J Zavin, O Karni-Katovitch, I Goldfracht, I Michael, SD Waldman, S Duvdevani, S Levenberg. “Human-engineered auricular reconstruction (hEAR) by 3D-printed molding with human-derived auricular and costal chondrocytes and adipose-derived mesenchymal stem cells”. Biofabrication. 14 (1), 0150103.  (2021)
     

24. I Redenski, S Guo, M Machour, A Szklanny, S Landau, B Kaplan, R I Lock, Y Gabet, D Egozi, G Vunjak-Novakovic, S Levenberg. “Engineered vascularized flaps, composed of polymeric soft tissue and live bone, repair complex tibial defects”. Advanced Functional Materials. 31(44). (2021)
     

25. S Landau, A Newman, S Edri, I Michael, S Ben-Shaul, Y Shandalov, T Ben-Arye, P Kaur, MH, Zheng, S Levenberg. “Investigating lymphangiogenesis in vitro and in vivo using engineered human lymphatic vessel networks”. PNAS, 118(31) (2021)
     

26. Luba Perry*, Shahar Ben-Shaul*,  S Landau*, and Shulamit Levenberg. “Co-Culture Systems for Vasculogenesis”. Vascularization for Tissue Engineering and Regenerative Medicine, Vascularization for Tissue Engineering and Regenerative Medicine, # Springer International Publishing AG. DOI 10.1007/978-3-319-21056-8_7-1. (2021)
     

27. S Guo, I Redenski, S Landau, A Szklanny, U Merdler, S Levenberg. “Prevascularized scaffolds bearing human dental pulp stem cells for treating complete spinal cord injury”. Advanced healthcare materials, 9 (20), 2000974.(2020)
     

28. S Guo, N Peretz, O Betzer,  S Landau, R Popovtzer, D Ofen, S Levenberg. “Extracellular Vesicles Tracking and Quantification Using CT and Optical Imaging in Rats”. Bioprotocol. 10 (11), e3635-e3635. (2020)
     

29. P.L. Graney, S Ben-Shaul, S Landau, A Bajpai, B Singh, J Eager, A Cohen, S Levenberg, K.L . Spiller. “Macrophages of diverse phenotypes drive vascularization of engineered tissues”. ScienceAdvances ,Vol.6,no.18,(2020)
     

30. T Ben-Arye, Y Shandalov, S Ben-Shaul, S Landau, Y Zagury, I Ianovici, N Lavon, S Levenberg. “Textured soy protein scaffolds enable the generation of three-dimensional bovine skeletal muscle tissue for cell-based meat”. Nature Food, 1-11. (2020)
     

31. S Ben Shaul, S Landau, U Merdler, S Levenberg. “Mature vasculature within engineered tissue promotes graft-host anastomosis and prevents graft thrombosis”. PNAS, 116 (8) 2955-2960;(2019)
     

32. S Landau, A Moriel, A Livne, H Zheng, E Bouchbinder, S Levenberg. “Tissue-level mechanosensitivity: Predicting and controlling the orientation of 3D vascular networks”. Nano Lett., 18 (12),7698–7708, (2018)
     

33. L Perry, S Landau, M.Y Flugelman , S Levenberg . “Genetically engineered vascularized muscle transplant enhances host neovascularization and myogenesis”. Communications Biology volume 1, Article number: 161 (2018) 
     

34. S Landau, S Ben Shaul, S Levenberg. “Oscillatory Strain Promotes Vessel Stabilization and Alignment through Fibroblast YAP‐Mediated Mechanosensitivity”. Advanced Science.DOI:10.1002/advs.201800506 (2018)
     

35. T Kaufman, B Kaplan, L Perry, Y Shandalov, S Landau, I Srugo, D Adel, S Levenberg.  “Innervation of an engineered muscle graft for reconstruction of muscle defects”. American Journal of Transplantation, DOI: 10.1111/ajt.14957 (2018)
     

36. S Landau, S Guo and S Levenberg. “Localization of Engineered Vasculature within 3D Tissue Constructs”; Front. Bioeng. Biotechnol, 2018.6:2. doi: 10.3389/fbioe..00002. (2018)
     

37. B Zohar, S Landau, S Levenberg. “Mechanical Regulation of Vascularization in Three-Dimensional Engineered Tissues”; Biophysical Regulation of Vascular Differentiation and Assembly, 37-49. (2018)
     

38. S Landau, A. Szklanny, Giselle C. Yeo, Y Shandalov, E Kosobrodova, AS Weiss, S Levenberg “Tropoelastin coated PLLA-PLGA scaffolds promote vascular network formation”. Biomaterials, 122;72-82. (2017)
     

39. D Rosenfeld, S Landau, Y Shandalov, N Raindel, A Freiman, E Shor, Y Blinder, H H. Vandenburgh, D J. Mooney, and S Levenberg. “Morphogenesis of 3D vascular networks is regulated by tensile forces”; PNAS 113;3215-3220. (2016)
     

40. A Lesman, D Rosenfeld, S Landau, S Levenberg. “Mechanical regulation of vascular network formation in engineered matrices”.  Advanced drug delivery reviews.  15;96:176-82 (2016)

 

*Co-first authors